PPI Pharmaceuticals
PPI Pharmaceuticals

Mining protein-protein interactions for targeted cancer drug discovery

Research targets

REPLACE inhibitors of the polo-box domain, in lead optimization with Phase I STTR support.

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Mission

To develop next-generation cancer therapeutics by utilizing novel technology to exploit protein-protein interactions.

Focus

Protein kinases deregulated in oncology indications — with emphasis on allosteric and non-catalytic PPI interfaces that conventional ATP-site drugs leave untouched.